Publications

Journal Article

Cysteine as a Multifaceted Player in Kidney, the Cysteine-Related Thiolome and Its Implications for Precision Medicine
MOLECULES, 27, 2022
Maria Joao Correia , Antonio B. Pimpao , Dalila G. F. Fernandes , Judit Morello , Catarina O. Sequeira , Joaquim Calado , Alexandra Maria Moita Antunes , Manuel S. Almeida , Patricia Branco , Emilia C. Monteiro , Joao B. Vicente , Jacinta Serpa , Sofia A. Pereira

Glycidamide and cis-2-butene-1,4-dial (BDA) as potential carcinogens and promoters of liver cancer - An in vitro study
FOOD AND CHEMICAL TOXICOLOGY, 166, 2022
Sofia Gouveia-Fernandes , Armanda Rodrigues , Carolina Nunes , Catarina Charneira , Joao Nunes , Jacinta Serpa , Alexandra Maria Moita Antunes

Identification of gallotannins and ellagitannins in aged wine spirits: A new perspective using alternative ageing technology and high-resolution mass spectrometry
FOOD CHEMISTRY, 382, 2022
Tiago A. Fernandes , Alexandra Maria Moita Antunes , Ilda Caldeira , Ofelia Anjos , Victor de Freitas , Laurent Fargeton , Benjamin Boissier , S Catarino , Sara Canas

Synthetic Red Blood Cell-Specific Glycolytic Intermediate 2,3-Diphosphoglycerate (2,3-DPG) Inhibits Plasmodium falciparum Development In Vitro
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 12, 2022
Ines Morais , Marcia M. Medeiros , Maria Carvalho , Judit Morello , Sara M. Teixeira , Suelma Maciel , Janice Nhantumbo , Ana Balau , Margarida T. G. Rosa , Fatima Nogueira , Joao Alexandre Rodrigues , Filomena A. Carvalho , Alexandra Maria Moita Antunes , Ana Paula Arez

A simple method to measure sulfonation in man using paracetamol as probe drug
SCIENTIFIC REPORTS, 11, 4 2021
Natalia Marto , Judit Morello , Alexandra Maria Moita Antunes , Sofia Azeredo , Emilia C. Monteiro , Sofia A. Pereira

The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies
PHARMACOLOGICAL RESEARCH, 165, 3 2021
Aline T. Marinho , Joana R. Batuca , Joana P. Miranda , Umbelina Caixas , Clara G. Dias , Teresa Branco , Karina Soto , Pedro F. Pinheiro , Mafalda Bourbon , M. Matilde Marques , Alexandra Maria Moita Antunes , Emilia C. Monteiro , Sofia A. Pereira

Tryptophanol-Derived Oxazolopyrrolidone Lactams as Potential Anticancer Agents against Gastric Adenocarcinoma
PHARMACEUTICALS, 14, 3 2021
Margarida Espadinha , Valentina Barcherini , Lidia Goncalves , Elies Molins , Alexandra Maria Moita Antunes , Maria M. M. Santos

Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine
MOLECULES, 26, 3 2021
Shrika G. Harjivan , Catarina Charneira , Ines L. Martins , Sofia A. Pereira , Guadalupe Espadas , Eduard Sabido , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography High Resolution Mass Spectrometry
FRONTIERS IN CHEMISTRY, 8, 1 2021
Beatriz T. Lopes , Maria Joao Caldeira , Helena Gaspar , Alexandra Maria Moita Antunes

Human Cystathionine gamma-Lyase Is Inhibited by S-Nitrosation: A New Crosstalk Mechanism between NO and H2S
ANTIOXIDANTS, 10, 2021
Dalila G. F. Fernandes , Joao Nunes , Catarina S. Tome , Karim Zuhra , Joao M. F. Costa , Alexandra Maria Moita Antunes , Alessandro Giuffre , Joao B. Vicente

Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes
MOLECULES, 25, 5 2020
Paula C. Alves , Patricia Rijo , Catarina Bravo , Alexandra Maria Moita Antunes , Vânia André

Novel Antibacterial Azelaic Acid BioMOFs
CRYSTAL GROWTH \& DESIGN, 20, 370-382 1 2020
Silvia Quaresma , Vânia André , Alexandra Maria Moita Antunes , Sergio M. F. Vilela , Georgiana Amariei , Ana Arenas-Vivo , Roberto Rosal , Patricia Horcajada , M. Teresa Duarte

Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21, 6 2020
Madalena Cipriano , Pedro F. Pinheiro , Catarina O. Sequeira , Joana S. Rodrigues , Nuno G. Oliveira , Alexandra Maria Moita Antunes , Matilde Castro , M. Matilde Marques , Sofia A. Pereira , Joana P. Miranda

16 alpha-Hydroxyestrone: Mass Spectrometry-Based Methodologies for the Identification of Covalent Adducts Formed with Blood Proteins
CHEMICAL RESEARCH IN TOXICOLOGY, 33, 2147-2156 8 2020
Catarina Charneira , João Pedro da Costa Nunes , Alexandra Maria Moita Antunes

Severe Acute Kidney Injury and Double Tubulopathy Due to Dual Toxicity Caused by Combination Antiretroviral Therapy
KIDNEY INTERNATIONAL REPORTS, 4, 494-499 3 2019
Karina Soto , Pedro Campos , Rita Manso , Alexandra Maria Moita Antunes , Judit Morello , Mark A. Perazella

Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study
CHEMICAL RESEARCH IN TOXICOLOGY, 32, 869-877 5 2019
Aline de Conti , Volodymyr Tryndyak , Linda S. VonTungeln , Mona I. Churchwell , Frederick A. Beland , Alexandra Maria Moita Antunes , Igor P. Pogribny

Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity
DRUG METABOLISM REVIEWS, 51, 76-90 1 2019
Aline T. Marinho , Joana P. Miranda , Umbelina Caixas , Catarina Charneira , Clara Goncalves-Dias , M. Matilde Marques , Emilia C. Monteiro , Alexandra Maria Moita Antunes , Sofia A. Pereira

Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease
NEPHRON, 143, 17-23 2019
Clara Goncalves-Dias , Judit Morello , M. Joao Correia , Nuno R. Coelho , Alexandra Maria Moita Antunes , Maria Paula de Macedo , Emilia C. Monteiro , Karina Soto , Sofia A. Pereira

Targeting Glutathione and Cystathionine beta-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation
NUTRIENTS, 11, 10 2019
Ines Santos , Cristiano Ramos , Cindy Mendes , Catarina O. Sequeira , Catarina S. Tome , Dalila G. H. Fernandes , Pedro Mota , Rita F. Pires , Donato Urso , Ana Hipolito , Alexandra Maria Moita Antunes , Joao B. Vicente , Sofia A. Pereira , Vasco D. B. Bonifacio , Sofia C. Nunes , Jacinta Serpa

A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications
FRONTIERS IN CHEMISTRY, 7, 7 2019
João Pedro da Costa Nunes , Catarina Charneira , Carolina Nunes , Sofia Gouveia-Fernandes , Jacinta Serpa , Judit Morello , Alexandra Maria Moita Antunes

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